First CRO to develop and validate a bioanalytical method with a LLOQ of 0.05 pg/mL.
Keystone Bioanalytical is the 1st CRO to develop and validate a bioanalytical method with a LLOQ of 0.05 pg/mL.
Keystone Bioanalytical is the 1st CRO with a SCIEX 7500 Triple Quad mass spectrometer, the most sensitive state-of-the-art mass spectrometers offered by AB SCIEX.
Keystone Bioanalytical is the 1st CRO with an AB SCIEX 6500 Triple Quad mass spectrometer with SelexION™ Technology and with multiple AB SCIEX 5500 mass spectrometers.
Keystone Bioanalytical is the only CRO to offer and utilize the AB SCIEX SelexION® interface. This enables Keystone Bionanalytical to provide an added dimension of selectivity.
AB SCIEX 6600 Triple TOF
The AB Sciex triple TOF is capable of high resolution (<10 ppm) mass spectroscopy with or without MS/MS for qualitative and/or quantitative analyses. The instrument provides accurate mass determinations for proteins and metabolites.
Thermo Fisher Q Exactive™ Hybrid Quadrupole-Orbitrap™ Mass Spectrometer
The liquid chromatography coupled with PDA and high-resolution mass spectrometer (LC-UV-HRMS) instruments are mainly used for in vitro and in vivo drug metabolite profiling and identification projects.
High Resolution ICP-MS for Trace Elemental Analysis
Thermo Element 2 high resolution mass spectrometer is capable of ultra-trace elemental analysis. ICP-MS is an essential analytical tool for bioanalysis for organometallics and inorganics, in general. Keystone was the first laboratory to validate an ICP-MS methods for BE studies and ANDA submissions. Keystone has recently added transition metal analysis capabilities for support of protein distribution studies.