Capabilities

Capabilities | Instrumentation | Facilities | Videos | Faqs 

First CRO to develop and validate a bioanalytical method with a LLOQ of 0.05 pg/mL.

Keystone Bioanalytical is the 1st CRO to develop and validate a bioanalytical method with a LLOQ of 0.05 pg/mL. 

First CRO with an AB SCIEX 5500 Triple Quad Mass Spectrometer

Keystone Bioanalytical is the 1st CRO with an AB SCIEX 5500 Triple Quad mass spectrometer with SelexION Technology and with multiple AB SCIEX 5500 mass spectrometers. The most sensitive state-of-the-art mass spectrometers offerred by AB SCIEX.

First CRO to equiped with the SelexION® Interface

Keystone Bioanalytical is the only CRO to offer and utilize the AB SCIEX SelexION® interface. This enables Keystone Bionanalytical to provide an added dimension of selectivity.

AB SCIEX 6600 Triple TOF

The AB Sciex triple TOF is capable of high resolution (<10 ppm) mass spectroscopy with or without MS/MS for qualitative and/or quantitative analyses. The instrument provides accurate mass determinations for proteins and metabolites.

ICP-MS for Trace Elemental Analysis

Agilent Series 7500cx is capable of ultra-trace elemental analysis. ICP-MS is an essential analytical tool for bioanalysis for organometallics and inorganics, in general. Keystone was the first laboratory to validate an ICP-MS methods for BE studies and ANDA submissions. Keystone has recently added transition metal analysis capabilities for suport of protein distribution studies.

Oligonucleotide Analysis

Keystone provides method development, validation, and analysis of oligonucleotides in biological matrices. The techniques uses cross hybridization with fluorescence PNA probes which affords quantitation of oligonucleotides to ≤1 ng/mL in plasma.

Who We Are

Keystone Bioanalytical is a Contract Research Organization (CRO) providing quantitative bioanalytical method development, validation and analysis for pharmaceutical and biotechnology companies. We perform GLP compliant and non-regulated (R&D) studies. more...

 

Quicklinks

Contact

Keystone Bioanalytical, Inc.

501 Dickerson Road

North Wales, PA 19454

ph: 215-699-8885

ph: 215-699-8899 

fax: 267-657-1331

info@keystonebioanalytical.com