List of Validated Assays

Keystone Bioanalytical provides an extensive set of  Validated Assays.

No. Parent Compound Method Matrix LLOQ
1 Acetyl-Coenzyme A LC/MS/MS Tumor Tissue 100 ng/g
2 ACTH (1-24) LC/MS/MS K2EDTA Human Plasma 0.5 ng/mL
3 ACTH(1-24) LC/MS/MS K2EDTA Monkey Plasma 0.05 ng/mL
4 ACTH(1-24) LC/MS/MS K2EDTA Rat Plasma 0.05 ng/mL
5 Agomelatine LC/MS/MS K2EDTA Human Plasma 0.05 ng/mL
6 Aldosterone LC/MS/MS Human Urine 0.1 ng/mL
7 Aldosterone LC/MS/MS K2EDTA Human Plasma 10 pg/mL
8 Almotriptan LC/MS/MS K2EDTA Human Plasma 0.5 ng/mL
9 Amphetamine (Chiral) LC/MS/MS Chiral K2EDTA Human Plasma 0.2 ng/mL
10 Angiotensin I LC/MS/MS K2EDTA Human Plasma 0.14 ng/mL
11 Angiotensin II Immunoassay K2EDTA Human Plasma 3.9 pg/mL
12 Arachidonic Acid LC/MS/MS Cerebrospinal Fluid 0.5 ng/mL
13 Arachidonic Acid LC/MS/MS K2EDTA Human Plasma 50 ng/mL
14 Arachidonic Acid, HETE, LTB4 LC/MS/MS Cell Culture Media 0.025 µM
15 Arachidonoyl 1-Glycerol LC/MS/MS Cerebrospinal Fluid 10 pg/mL
16 Arachidonoyl 1-Glycerol LC/MS/MS K2EDTA Human Plasma 0.5 ng/mL
17 Arachidonoyl 2-Glycerol LC/MS/MS Cerebrospinal Fluid 10 pg/mL
18 Arachidonoyl 2-Glycerol LC/MS/MS K2EDTA Human Plasma 0.5 ng/mL
19 Arachidonoyl Ethanolamide LC/MS/MS Cerebrospinal Fluid 1 pg/mL
20 Arachidonoyl Ethanolamide LC/MS/MS K2EDTA Human Plasma 0.05 ng/mL
21 Arachidonoyl Taurine LC/MS/MS Cerebrospinal Fluid 100 pg/mL
22 Arachidonoyl Taurine LC/MS/MS K2EDTA Human Plasma 0.5 ng/mL
23 Arginase Activity Immunoassay Juman Serum 0.06 nM
24 Arginine LC/MS/MS Heparinized Human Plasma 1 µg/mL
25 Ascorbic Acid  LC/MS/MS Human Tissue and Lavage Fluid 20 ng/mL
26 Atorvastatin, 2-Hydroxy Atorvastatin, 4-Hydroxy Atorvastatin  LC/MS/MS K2EDTA Human Plasma 0.2 ng/mL
27 Betaxolol LC/MS/MS K2EDTA Human Plasma 0.5 ng/mL
28 Bosentan LC/MS/MS K2EDTA Human Plasma 5 ng/mL
29 Bosenton (Hydroxy Metabolite) LC/MS/MS K2EDTA Human Plasma 0.5 ng/mL
30 Brinzolamide LC/MS/MS K2EDTA Human Plasma 0.05 µg/mL
31 Bromide ICP-MS Na Heparin Human Plasma 0.5 µg/mL
32 Budesonide LC/MS/MS K2EDTA Human Plasma 5 pg/mL
33 Buprenorphine LC/MS/MS K2EDTA Human Plasma 20 pg/mL
34 Buprenorphine LC/MS/MS Human Urine 20 pg/mL
35 Buprenorphine Hemiadipate LC/MS/MS Human Urine 0.5 pg/mL
36 Buprenorphine Hemiadipate LC/MS/MS K2EDTA Human Plasma 0.5 pg/mL
37 Buprenorphine Hemiadipate LC/MS/MS K2EDTA Dog Plasma 0.5 pg/mL
38 Caffeine LC/MS/MS K2EDTA Human Plasma 5 ng/mL
39 Caffeine LC/MS/MS Human Serum 0.05 µg/mL
40 Calcium ICP/MS Human Serum 10 µg/mL
41 Carbamazepine LC/MS/MS K2EDTA Human Plasma 0.1 µg/mL
42 Carbamazepine (10,11-Epoxide Metabolite) LC/MS/MS K2EDTA Human Plasma 0.025 µg/mL
43 Cebranopadol and Metabolites LC/MS/MS K2EDTA Human Plasma 0.5 pg/mL
44 Ceftaroline and Metabolites LC/MS/MS K2EDTA Human Plasma 50 ng/mL
45 Ceftaroline and Metabolites LC/MS/MS Human Urine 0.5 µg/mL
46 Chlorpheniramine (Chiral) LC/MS/MS Chiral K2EDTA Human Plasma 0.05 ng/mL
47 Chlorpromazine LC/MS/MS K2EDTA Human Plasma 0.5 ng/mL
48 Citalopram LC/MS/MS K2EDTA Human Plasma 1 ng/mL
49 Citalopram (Desmethyl Metabolite) LC/MS/MS K2EDTA Human Plasma 1 ng/mL
50 Colistin LC/MS/MS K2EDTA Rat Plasma 10 ng/mL
51 Colistin LC/MS/MS Rat Lung 100 ng/g
52 Colistin LC/MS/MS Human Urine 10 ng/mL
53 Colistin Methanesulfonate (Free and Total) LC/MS/MS K2EDTA Rat Plasma 10 ng/mL
54 Colistin Methanesulfonate (Free and Total) LC/MS/MS Rat Lung 100 ng/g
55 Colistin Methanesulfonate (Free and Total) LC/MS/MS Human Urine 10 ng/mL
56 Cortisol LC/MS/MS K2EDTA Human Plasma 0.25 ng/mL
57 Dialkyl Phosphates LC/MS/MS Human Urine .5 ng/mL
58 Digoxin LC/MS/MS K2EDTA Human Plasma 0.1 ng/mL
59 Digoxin LC/MS/MS Human Urine 1 ng/mL
60 Dimethyl Arginine LC/MS/MS Human Serum 10 ng/mL
61 Diphenylhdramine LC/MS/MS K2EDTA Human Plasma 0.1 ng/mL
62 Docohexaenoic Acid LC/MS/MS Cerebrospinal Fluid 0.5 ng/mL
63 Docohexaenoic Acid LC/MS/MS K2EDTA Human Plasma 50 ng/mL
64 Dopamine LC/MS/MS K2EDTA Human Plasma 10 pg/mL
65 Dronedarone LC/MS/MS K2EDTA Human Plasma 0.2 ng/mL
66 Dronedarone (Desbutyl Metabolite) LC/MS/MS K2EDTA Human Plasma 0.2 ng/mL
67 Drug Antibody Conjugate LC/MS/MS K2EDTA Human Plasma 10 nM
68 Duloxetine LC/MS/MS K2EDTA Human Plasma 0.5 ng/mL
69 Entecavir LC/MS/MS K2EDTA Human Plasma 10 pg/mL
70 Epinephrine LC/MS/MS K2EDTA Human Plasma 10 pg/mL
71 Flecainide LC/MS/MS K2EDTA Human Plasma 1 ng/mL
72 Fluoride IC/ICP/MS Human Serum 10 ng/mL
73 Flupirtine LC/MS/MS K2EDTA Human Plasma 2 ng/mL
74 Fluticasone Propionate LC/MS/MS K2EDTA Human Plasma 2 pg/mL
75 Formeterol LC/MS/MS NaF/K2C2O4 Human Plasma  0.4 pg/mL
76 GDP Fucose LC/MS/MS Cell Culture Media 5 ng/mL
77 Glutarate,  2-Hydroxy LC/MS/MS Cell Culture Media 2.5 ng/mL
78 Hydromorphone LC/MS/MS K2EDTA Human Plasma 0.05 ng/mL
79 Hydroxybutyric Acid LC/MS/MS Human Urine 0.25 µg/mL
80 Idebenone LC/MS/MS K2EDTA Human Plasma 0.05 ng/mL
81 Idebenone, Total LC/MS/MS K2EDTA Human Plasma 50 ng/mL
82 Inositol LC/MS/MS Human Serum 1 µg/mL
83 Iron Sucrose ICP-MS Human Serum 1 ng/mL
84 Ivabradine LC/MS/MS K2EDTA Human Plasma 0.01 ng/mL
85 Ivermectin B1a LC/MS/MS K2EDTA Human Plasma 0.4 ng/mL
86 Ivermectin B1b LC/MS/MS K2EDTA Human Plasma 40 pg/mL
87 Ketoconazole LC/MS/MS K2EDTA Human Plasma 0.05 µg/mL
88 Ketoprofen LC/MS/MS K2EDTA Human Plasma 10 ng/mL
89 Levothyroxine (Free T4) Immunoassay Human Serum 0.3 ng/mL
90 Levothyroxine (Total T4) LC/MS/MS Human Serum 10 ng/mL
91 Liothyronine (Free T3) Immunoassay Human Serum 1 pg/mL
92 Liothyronine (Total T3) LC/MS/MS Human Serum 0.1 ng/mL
93 Lornoxicam LC/MS/MS K2EDTA Human Plasma 2 ng/mL
94 Lovastatin , Lovastatin Hydroxy Acid  LC/MS/MS K2EDTA Human Plasma 0.5 ng/mL
95 Lysophosphatidyl acid  LC/MS/MS K2EDTA Mouse Plasma 10 nM
96 Lysophosphatidylcholine LC/MS/MS K2EDTA Mouse Plasma 10 nM
97 Malonyl Coenzyme A LC/MS/MS Tissue 10 ng/g
98 Melatonin LC/MS/MS K2EDTA Human Plasma 1 pg/mL
99 Methotrexate LC/MS/MS K2EDTA Human Plasma 1 ng/mL
100 Methylphenidate LC/MS/MS K2EDTA Human Plasma 0.1 ng/mL
101 Methylphenidate LC/MS/MS K2EDTA Human Plasma 0.1 ng/mL
102 Mevalonic Acid LC/MS/MS Human Urine 5 ng/mL
103 Mometasone Furoate LC/MS/MS K2EDTA Human Plasma 2 pg/mL
104 Morphine LC/MS/MS K2EDTA Human Plasma 0.5 ng/mL
105 Morphine Glucuronide LC/MS/MS K2EDTA Human Plasma 2 ng/mL
106 Naloxone LC/MS/MS K3EDTA Human Plasma 2 pg/mL
107 Naloxone LC/MS/MS K2EDTA Human Plasma 1 pg/mL
108 Naloxone LC/MS/MS Human Urine 5 pg/mL
109 Naloxone-3-Glucuronide LC/MS/MS K2EDTA Human Plasma 50 pg/mL
110 Nebivolol, Chiral LC/MS/MS K2EDTA Human Plasma 10 pg/mL
111 Nebivolol, Total LC/MS/MS K2EDTA Human Plasma 0.5 ng/mL
112 Norbuprenorphine LC/MS/MS K2EDTA Human Plasma 20 pg/mL
113 Norbuprenorphine LC/MS/MS Human Urine 20 pg/mL
114 Norepinephrine LC/MS/MS K2EDTA Human Plasma 10 pg/mL
115 Nucleotides LC/MS/MS Cell Culture Media 5 ng/mL
116 Nucleotides LC/MS/MS Human Serum 5 ng/mL
117 Oleoyl Ethanolamide LC/MS/MS Cerebrospinal Fluid 5 pg/mL
118 Oleoyl Ethanolamide LC/MS/MS K2EDTA Human Plasma 0.25 ng/mL
119 Oleoyl Taurine LC/MS/MS Cerebrospinal Fluid 100 pg/mL
120 Oleoyl Taurine LC/MS/MS K2EDTA Human Plasma 0.5 ng/mL
121 Oxycodone LC/MS/MS K2EDTA Human Plasma 0.5 ng/mL
122 Palmitic Acid LC/MS/MS Tumor Tissue 100 ng/g
123 Palmitoyl Ethanoamide LC/MS/MS Cerebrospinal Fluid 5 pg/mL
124 Palmitoyl Ethanoamide LC/MS/MS K2EDTA Human Plasma 0.25 ng/mL
125 Palmitoyl Taurine LC/MS/MS Cerebrospinal Fluid 100 pg/mL
126 Palmitoyl Taurine LC/MS/MS K2EDTA Human Plasma 0.5 ng/mL
127 Phenylephrine LC/MS/MS K2EDTA Human Plasma 10 pg/mL
128 Plasma Renin Activity LC/MS/MS K2EDTA Human Plasma 0.05 ng/mL/hr
129 Platinum ICP-MS K2EDTA Human Plasma 1 µg/mL
130 Poloxamer LC/MS/MS K2EDTA Dog Plasma 1 µg/mL
131 Potassium ICP-MS Human Urine 20 µg/mL
132 Pravastatin LC/MS/MS K2EDTA Human Plasma 0.5 ng/mL
133 Pseudoephedrine LC/MS/MS K2EDTA Human Plasma 1 ng/mL
134 Pterostilbene LC/MS/MS Human Serum 0.5 ng/mL
135 Pyruvic Acid LC/MS/MS Human Urine 0.05 µg/mL
136 Rosuvastatin, N-Desmethyl Rosuvastatin  LC/MS/MS K2EDTA Human Plasma 0.2 ng/mL
137 Salmeterol LC/MS/MS K2EDTA Human Plasma 2 pg/mL
138 Selenium ICP/MS Human Serum 100 ng/mL
139 Sertraline LC/MS/MS K2EDTA Human Plasma 1 ng/mL
140 Sertraline (Desmethyl Metabolite) LC/MS/MS K2EDTA Human Plasma 1 ng/mL
141 Silcone ICP/MS K2EDTA Human Plasma 10 µg/mL
142 Sildenafil and N-Desmethyl Sildenafil LC/MS/MS Sodium Heparin Human Plasma 1 ng/mL
143 Simvastatin, Simvastatin Hydroxy Acid  LC/MS/MS K2EDTA Human Plasma 0.5 ng/mL
144 Sitagliptin LC/MS/MS K2EDTA Human Plasma 1 ng/mL
145 Stearoyl Taurine LC/MS/MS Cerebrospinal Fluid 100 pg/mL
146 Stearoyl Taurine LC/MS/MS K2EDTA Human Plasma 0.5 ng/mL
147 Thyrotropin Stimulating Hormone (TSH) Immunoassay Human Serum 0.2 µIU/mL
148 Tiotropium LC/MS/MS K2EDTA Human Plasma 0.5 pg/mL
149 Urea LC/MS/MS KOx/NaF Human Plasma 100 µg/mL
150 Urea LC/MS/MS Human Bronchoalveolar Lavage 0.2 µg/mL
151 Uric Acid LC/MS/MS Human Tissue and Lavage Fluid 5 ng/mL
152 Valsartan LC/MS/MS K2EDTA Human Plasma 5 ng/mL
153 Venlafaxine LC/MS/MS K2EDTA Human Plasma 1 ng/mL
154 Venlafaxine (Desmethyl Metabolite) LC/MS/MS K2EDTA Human Plasma 1 ng/mL
155 Vilazodone LC/MS/MS K2EDTA Rat Plasma 2 ng/mL
156 Vilazodone LC/MS/MS K2EDTA Rabbit Plasma 2 ng/mL
157 Vilazodone (M17 Metabolite) LC/MS/MS K2EDTA Rat Plasma 1 ng/mL
158 Vilazodone (M17 Metabolite) LC/MS/MS K2EDTA Rabbit Plasma 1 ng/mL
159 Vitamin B6 LC/MS/MS K2EDTA Human Plasma 0.2 ng/mL
160 Vitamin D2,  1, 25-Dihydroxy  LC/MS/MS Human Serum 10 pg/mL
161 Vitamin D2, 25-Hydroxy LC/MS/MS Human Serum 5 ng/mL
162 Vitamin D3 LC/MS/MS K2EDTA Human Plasma 0.5 ng/mL
163 Vitamin D3,  1, 25-Dihydroxy  LC/MS/MS Human Serum 10 pg/mL
164 Vitamin D3, 25-Hydroxy LC/MS/MS Human Serum 5 ng/mL
165 Vitamin D3, 25-Hydroxy LC/MS/MS K2EDTA Human Plasma 1 ng/mL
166 Bile Acids LC/MS/MS K2EDTA Human Plasma 10 ng/mL
167 Bile Acids LC/MS/MS Feces 10 ng/mL
168 Factor Xa Chromogenic Human Serum 0.1 IU
169 Factor IIa Chromogenic Human Serum

0.02 IU

170
 NAD+ (Nicotinamide adenine dinucleotide)
LC/MS/MS Human Blood

100 ng/mL

171
Nicotinamide Riboside (NR)
LC/MS/MS Human Blood

100 ng/mL

172
Oxymetazoline Impurity A
LC/MS/MS Minipig Plasma

0.1 ng/mL

173
Roflumilast and Roflumilast N-Oxide
LC/MS/MS Li Heparin Human Plasma

0.1 ng/mL

174
Vildagliptin
LC/MS/MS K2EDTA Human Plasma

1 ng/mL

175
6-Mercaptopurine
LC/MS/MS K2EDTA Human Plasma

1 ng/mL

176
Baclophen
LC/MS/MS K2EDTA Human Plasma

0.025 ng/mL

177
Levomilnacipram
LC/MS/MS K2EDTA Human Plasma

0.025 ng/mL

178
Ceftazidine
LC/MS/MS K2EDTA Human Plasma

40 ng/mL

179
Avibactam
LC/MS/MS K2EDTA Human Plasma

10 ng/mL

180
Fosfomycin
LC/MS/MS K2EDTA Human Plasma

1 µg/mL

181
Carbocysteine
LC/MS/MS K2EDTA Human Plasma

30 ng/mL

182
Fosfomycin
LC/MS/MS Human Urine

2 µg/mL

183
Methylnicotinamide
LC/MS/MS Human Urine

0.5 µg/mL

 

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Keystone Bioanalytical is a Contract Research Organization (CRO) providing quantitative bioanalytical method development, validation and analysis for pharmaceutical and biotechnology companies. We perform GLP compliant and non-regulated (R&D) studies. more...

 

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Keystone Bioanalytical, Inc.

501 Dickerson Road

North Wales, PA 19454

ph: 215-699-8885

ph: 215-699-8899 

fax: 267-657-1331

info@keystonebioanalytical.com